Directory

Discover detailed profiles of PoC companies.

BeNatureBioLab Co., Ltd.

Eco-Friendly Nano Platform for Health & Beauty Market

Specialization

Eco-Friendly HME-DDS Platform
Drug Delivery System
Nano Formulation Technology

Keywords

HME-DDS
Hot Melt Extrusion
Nano Platform

BeNatureBioLab develops HME-DDS™, an eco-friendly nano platform based on Hot Melt Extrusion and Drug Delivery System technology.
HME-DDS™ enables solvent-free processing and improves the bioavailability of natural products, synthetic drugs, and macromolecules.
The platform can be applied to pharmaceuticals, functional foods, cosmetics, and marine-derived materials.
BeNatureBioLab’s strategy is “Pharma first, scalable to Beauty & Health-first”, expanding from natural products to biopharmaceuticals.

(1) Owned Technology

Solvent-free HME-DDS™ nano formulation technology.
Molecular-level amorphous stabilization within a polymer lattice.
High-loading drug delivery matrix technology with up to 50% active ingredient loading.
Low-temperature and low-pressure hybrid HME process.
Material-specific screw configuration and process optimization database.
HME-DDS™ + 3D printing technology for personalized drug and nutrition delivery.

(2) Applied Products

HME-DDS™ Platform
- Eco-friendly continuous process for enhancing solubility, stability, and absorption.
HME-DDS-3DP™
- 3D printing-based personalized formulation platform.
- Enables customized release control and dosage design.
ECOSOLUTION
- Water-soluble extract solution for cosmetics and functional ingredients.
ECOSPHERE
- Powder-type cosmetic material with enhanced formulation stability and skin absorption.
Functional Food / Pharma Pipelines
- Benign prostatic hyperplasia, sarcopenia, GLP-1 oral formulation, and health-functional food applications.

(1) Problem Definition / Development Background

Conventional formulation processes often rely on expensive solvents and bulky excipients.
Many active ingredients have poor solubility, low absorption, and limited bioavailability.
Traditional micronization or solvent-based dissolution methods can cause recrystallization and limited absorption improvement.
Food, cosmetics, and pharmaceutical markets need eco-friendly, high-efficiency formulation technologies that reduce cost while improving performance.

(2) Value Proposition / Solution

HME-DDS™ provides a solvent-free and by-product-free formulation process.
The technology improves bioavailability by controlling molecular structure and preventing recrystallization.
It can reduce excipient use, increase active ingredient loading, and create smaller dosage forms.
BeNatureBioLab supports scalable value creation through ingredients, products, CDMO, plant supply, and licensing.

Eco-Friendly Process: Solvent-free and by-product-free continuous process.
Improved Bioavailability: Up to 10x absorption improvement, with selected cases showing much higher enhancement.
Cost Savings: Potential cost savings of up to 50x depending on process and material.
High Loading Efficiency: High-density matrix can contain up to 50% active ingredients.
Low-Temperature Process: Processes heat-sensitive natural products, peptides, polymers, and bio-materials.
Strong IP & Research Base: 17 patent registrations, 13 patent applications, and 100+ SCI papers.
Certified Technology: Acquired NET certification and ISO 14001, ISO 9001, and ISO 22716 certifications.

Established in 2020.
Secured KRW 1.3B seed investment.
Completed GMP manufacturing facility and obtained HACCP.
Selected as Chuncheon’s first Deep Tech TIPS company.
Acquired New Excellent Technology, NET, certification.
Participated in CES and BIO USA.
Achieved first-half BEP in 2025.
Received awards including the Minister of SMEs and Startups Award, Gangwon Governor’s Award, and Intergreen CnA Excellence Award.
Manufacturing facility supports maximum daily production capacity of 5,000 kg.

(1) PoC Progress

Conducting NDA and PoC activities across food, cosmetics, and pharmaceutical sectors.
Partnership references include CJ, Amorepacific, Chong Kun Dang, Daewoong Pharmaceutical, and overseas partners.
Cosmetic contract signed, device purchase agreement under discussion after PoC, and multiple clinical/preclinical studies planned for 2026.

(2) Global Expansion

BeNatureBioLab plans to expand from Gangwon to national hubs including Osong, Songdo, Daejeon, and Gangwon.
Global expansion targets include China, Japan, the United States, and the European Union.
The company established a subsidiary in Nanjing, China, and plans further expansion to Japan and the U.S.
Business model includes B2B ingredient supply, B2C branded products, CDMO, plant equipment supply, technology licensing, and royalty revenue.